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Leukemoid reaction in amoebic liver abscess

R Avasthi1, S Agarwal, B K Ram

  • 1Department of Medicine, University College of Medical Sciences, Shahdara, Delhi.

Indian Journal of Medical Sciences
|March 1, 1995
PubMed
Summary

This case study describes an amoebic liver abscess presenting with jaundice and a leukemoid reaction. Metronidazole treatment successfully resolved the condition, normalizing the patient's blood counts and liver function.

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Area of Science:

  • Hepatology
  • Infectious Diseases
  • Hematology

Background:

  • Amoebic liver abscess (ALA) is a serious complication of Entamoeba histolytica infection.
  • Leukemoid reactions, characterized by elevated white blood cell counts, can occur in various inflammatory and infectious conditions.
  • Jaundice as a presenting feature of ALA, while not uncommon, necessitates thorough investigation.

Observation:

  • A patient presented with clinical signs of jaundice.
  • Diagnostic workup revealed an amoebic liver abscess.
  • The patient exhibited a concurrent leukemoid reaction in their blood work.

Findings:

  • Treatment with metronidazole led to a significant improvement in the patient's overall condition.
  • Post-treatment blood counts normalized, resolving the leukemoid reaction.
  • Liver function tests returned to normal ranges, indicating successful abscess resolution.

Implications:

  • This case highlights the importance of considering ALA in patients with jaundice and leukemoid reactions.
  • Metronidazole is an effective therapeutic agent for amoebic liver abscess.
  • Prompt diagnosis and treatment are crucial for favorable outcomes in ALA.

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