Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Palpable purpura: an algorithmic approach

G L Stevens¹, H M Adelman, P M Wallach

¹University of South Florida College of Medicine, Tampa, USA.

American Family Physician

|October 1, 1995

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Use of a committee review process to improve the quality of course examinations.

Advances in health sciences education : theory and practice·2006

Same author

A man with palpable purpuric hand lesions.

Hospital practice (1995)·2003

Same author

Standardized patients' perceptions about their own health care.

Teaching and learning in medicine·2001

Same author

An obese man with anxiety, sweating, and headache.

Hospital practice (1995)·2001

Same author

Carcinoma arising in epidermoid cyst: a case series and aetiological investigation of human papillomavirus.

The British journal of dermatology·2001

Same author

A man with a history of skin lesions and seizures.

Hospital practice (1995)·2001

Same journal

For Post-stent Patients With Atherosclerotic Coronary Vascular Disease Who Are Taking an Anticoagulant, Adding Aspirin Worsens Outcomes.

American family physician·2026

Same journal

Nausea and Vomiting During Pregnancy.

American family physician·2026

Same journal

Metabolic Dysfunction-Associated Steatotic Liver Disease: Diagnosis and Management.

American family physician·2026

Same journal

Aerobic Exercise Is the Better Exercise Modality for Knee Osteoarthritis.

American family physician·2026

Same journal

Overscreening Leads to Overdiagnosis of MASLD.

American family physician·2026

Same journal

Type 2 Diabetes: Outpatient Insulin Management.

American family physician·2026

See all related articles

Palpable purpura is often caused by drug reactions, infections, or autoimmune diseases. Diagnosis may require lab tests and skin biopsy if the cause isn't clear from initial examination.

Area of Science:

Dermatology
Immunology
Pathology

Background:

Palpable purpura is a clinical sign frequently associated with cutaneous vasculitis.
Identifying the underlying cause of palpable purpura is crucial for appropriate management.
Common triggers include drug reactions, infections, and collagen vascular diseases.

Purpose of the Study:

To review the common causes and diagnostic approaches for palpable purpura.
To highlight the role of history, physical examination, laboratory investigations, and skin biopsy in diagnosis.
To discuss treatment options for palpable purpura when necessary.

Main Methods:

Review of literature on cutaneous vasculitis and palpable purpura.
Analysis of diagnostic criteria and therapeutic strategies.

Related Experiment Videos

Emphasis on clinical presentation and etiological factors.

Main Results:

Cutaneous vasculitis is the most common identifiable cause of palpable purpura.
History and physical examination often reveal the cause.
Laboratory investigations and skin biopsy are essential when the etiology is unclear.
Many cases are idiopathic and self-limited.

Conclusions:

Palpable purpura necessitates a thorough diagnostic workup to identify underlying causes.
Early identification of triggers like drug reactions or infections guides treatment.
Pharmacological interventions including dapsone, colchicine, or corticosteroids are effective when treatment is indicated.