Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Limb-sparing therapy for soft tissue sarcomas

R E Pollock1

  • 1Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Current Opinion in General Surgery
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Verticillin A Inhibits Leiomyosarcoma and Malignant Peripheral Nerve Sheath Tumor Growth via Induction of Apoptosis.

Clinical & experimental pharmacology·2017
Same author

Molecular prognosticators of complex karyotype soft tissue sarcoma outcome: a tissue microarray-based study.

Annals of oncology : official journal of the European Society for Medical Oncology·2009
Same author

Postoperative nomogram for survival of patients with retroperitoneal sarcoma treated with curative intent.

Annals of oncology : official journal of the European Society for Medical Oncology·2009
Same author

Complete soft tissue sarcoma resection is a viable treatment option for select elderly patients.

Annals of surgical oncology·2009
Same author

Outcome of locally recurrent and metastatic angiosarcoma.

Annals of surgical oncology·2009
Same author

Reliable establishment of human sarcoma xenografts in the nude rat.

Sarcoma·2008
Same journal

Sensitivity versus cost effectiveness in postoperative follow-up for colorectal cancer.

Current opinion in general surgery·1994
Same journal

Adjuvant radiation for rectal cancer: when and with what?

Current opinion in general surgery·1994
Same journal

Screening for colorectal cancer.

Current opinion in general surgery·1994
Same journal

Colorectal.

Current opinion in general surgery·1994
Same journal

The management of acute respiratory failure.

Current opinion in general surgery·1994
Same journal

The place for curative surgical procedures in the treatment of sporadic and familial Zollinger-Ellison syndrome.

Current opinion in general surgery·1994
See all related articles

Limb salvage surgery for extremity soft tissue sarcoma has evolved, incorporating neoadjuvant chemotherapy, surgical resection, and radiotherapy. Microvascular free tissue transfer enhances functional outcomes in these rare tumors.

Area of Science:

  • Orthopedics
  • Surgical Oncology
  • Reconstructive Surgery

Background:

  • Extremity soft tissue sarcoma treatment has shifted from amputation to limb salvage.
  • Multimodality therapy is the current standard, involving chemotherapy, surgery, and radiation.
  • Microvascular techniques have improved resection scope and functional outcomes.

Purpose of the Study:

  • To discuss recent advances in the management of extremity soft tissue sarcoma.
  • To highlight the role of multimodality limb salvage procedures.
  • To emphasize the impact of microvascular free tissue transfer.

Main Methods:

  • Review of current multimodality treatment protocols for soft tissue sarcoma.
  • Discussion of surgical techniques, including negative margin resection.

Related Experiment Videos

  • Integration of neoadjuvant chemotherapy and radiotherapy.
  • Application of microvascular-dependent free tissue transfer.

    • Main Results:

    • Limb salvage procedures offer improved functional outcomes compared to radical resection.
    • Negative margin surgical resection is crucial for effective treatment.
    • Microvascular free tissue transfer significantly enhances the scope and functional results of resection.
    • Recent advances have further refined these limb-sparing approaches.

    Conclusions:

    • Effective therapy for extremity soft tissue sarcoma relies on a multimodality limb salvage approach.
    • Microvascular free tissue transfer is a key technique for optimizing functional outcomes.
    • Continued research and advancements are vital for improving outcomes in these rare tumors.