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Immunophilins and the nervous system

S H Snyder1, D M Sabatini

  • 1Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Nature Medicine
|January 1, 1995
PubMed

The search for immunosuppressant drugs to increase the success of organ transplantation led to the discovery of the immunophilins, proteins that interface with a range of signal transduction systems inside cells, especially in the nervous and immune systems. Here we review how these interesting molecules work and consider their therapeutic potential.

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