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Typhoid fever with very high transaminase levels
1Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara.
The Turkish Journal of Pediatrics
|April 1, 1995
Summary
Typhoid fever can present with rare complications like severe intravascular hemolysis and glomerulonephritis alongside hepatitis. This case highlights diagnostic challenges in pediatric enteric fever.
Area of Science:
- Pediatrics
- Infectious Diseases
- Nephrology
Background:
- Typhoid fever is a common infection in developing nations.
- Hepatic involvement is observed in 50% of patients with typhoid fever.
- Intravascular hemolysis and renal involvement are rare complications of typhoid fever.
Observation:
- A 10-year-old child with enteric fever presented with hepatitis.
- The patient also exhibited severe intravascular hemolysis.
- Glomerulonephritis was diagnosed in the patient.
Findings:
- This case presents a rare combination of hepatitis, severe intravascular hemolysis, and glomerulonephritis in a single patient with typhoid fever.
- The co-occurrence of these conditions is highly unusual.
- The clinical presentation posed significant diagnostic challenges.
Implications:
- Recognizing these rare presentations is crucial for timely diagnosis and management of typhoid fever.
- This case underscores the diverse clinical spectrum of enteric fever.
- Further research may elucidate the mechanisms behind these rare complications.