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["Blue" variant of naevus spilus]
P Kiene1, J P Brodersen, R Fölster-Holst
1Universitäts-Hautklinik, Kiel.
Summary
This case report details an unusual facial pigmented lesion in a 29-year-old female, diagnosed as agminated blue nevi with lentigo simplex. Histopathology confirmed dermal melanocytosis and multiple blue nevi, an uncommon variant of speckled lentiginous nevus.
Area of Science:
- Dermatopathology
- Dermatology
- Oncology
Background:
- Pigmented lesions require accurate clinical and histological assessment for diagnosis.
- Distinguishing benign nevi from malignant melanoma is crucial in dermatopathology.
- Unusual presentations of melanocytic lesions pose diagnostic challenges.
Observation:
- A 29-year-old female presented with a facial pigmented lesion clinically resembling nevus spilus.
- Histological examination revealed dermal melanocytosis and multiple blue nevi with a lentiginous component.
- Immunohistochemistry using S100 protein and HMB45 confirmed the melanocytic nature of the infiltrate.
Findings:
- The lesion was interpreted as agminated blue nevi associated with lentigo simplex.
- This represents an unusual variant of a speckled lentiginous nevus.
- The combination of dermal melanocytosis, blue nevi, and lentigo simplex is rare.
Implications:
- This case expands the spectrum of presentations for benign melanocytic proliferations.
- Accurate histopathological diagnosis is essential for managing such unusual pigmented lesions.
- Understanding rare variants aids in differential diagnosis and patient management in dermatology.