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Updated: Aug 18, 2026

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
Published on: August 13, 2019
Vertical guided bone-graft augmentation in a new canine mandibular model
O T Jensen1, R O Greer, L Johnson
1Department of Surgical Dentistry, University of Colorado School of Dentistry, Denver, USA.
Abstract:
Using the mandibular inferior border of four fox hounds from an extraoral approach, six high-profile Brånemark implants were placed in each animal and bone grafted. Graft materials studied included demineralized freeze-dried allograft with and without irradiation sterilization (3.8 x 10(4) Gy), corticocancellous iliac autograft, blood clot, and a control. Corticocancellous grafts were studied with and without expanded polytetrafluoroethylene (EPTFE) barriers. The barrier function improved both graft volume incorporated and bone-implant interface contact. The autograft performed better than the allograft. Irradiation of the allograft did not appear to affect graft performance. The barrier functioned to improve graft incorporation for augmentation and interface contact and gives credence to the use of barriers in conjunction with vertical augmentation grafting of jawbone.

