Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Antibiotic resistance in bacteria

F E Berkowitz1

  • 1Department of Pediatrics, Emory University School of Medicine, Atlanta GA 30303, USA.

Southern Medical Journal
|August 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acute liver failure caused by isoniazid in a child receiving carbamazepine.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·1998
Same author

Quadriplegia complicating Escherichia coli meningitis in a newborn infant: case report and review of 22 cases of spinal cord dysfunction in patients with acute bacterial meningitis.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·1997
Same author

Hepatosplenic cat-scratch disease and abdominal pain.

The Pediatric infectious disease journal·1997
Same author

Neonatal Torulopsis glabrata fungemia.

Southern medical journal·1997
Same author

Infective endocarditis in neonates.

Clinical pediatrics·1995
Same author

Third generation cephalosporin-resistant gram-negative bacilli in the feces of hospitalized children.

The Pediatric infectious disease journal·1995

Antibiotic resistance is a growing medical crisis driven by rapid bacterial multiplication and genetic adaptability. This resistance, facilitated by antibiotic presence, allows resistant strains to dominate, impacting key pathogens.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Pharmacology

Background:

  • Antibiotic resistance poses a significant global health threat.
  • Bacteria develop resistance through rapid multiplication, genetic mutation, and gene transfer.
  • Mechanisms include reduced drug entry, increased drug efflux, and enzymatic drug inactivation.

Purpose of the Study:

  • To summarize the mechanisms and implications of antibiotic resistance in bacterial pathogens.
  • To highlight the role of selective pressure in the prevalence of resistant strains.

Main Methods:

  • Literature review of bacterial resistance mechanisms.
  • Analysis of factors contributing to the spread of antibiotic resistance.
  • Identification of key human pathogens exhibiting resistance.

Related Experiment Videos

Main Results:

  • Bacteria employ biochemical strategies to resist antibiotics, such as preventing drug entry or inactivating the drug.
  • Antibiotic presence in human and animal environments creates selective pressure favoring resistant bacteria.
  • Numerous important pathogens, including Streptococcus pneumoniae and Mycobacterium tuberculosis, demonstrate resistance.

Conclusions:

  • Antibiotic resistance is a complex phenomenon driven by bacterial adaptability and environmental factors.
  • The emergence and spread of resistant bacteria represent a critical challenge in modern medicine.
  • Understanding resistance mechanisms is crucial for developing effective therapeutic strategies.