Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Growth hormone and reproduction

R Homburg¹, J Farhi

¹Department of Obstetrics and Gynecology, Golda Medical Center, Petah Tikva, Israel.

Current Opinion in Obstetrics & Gynecology

|June 1, 1995

Summary

Growth hormone (GH) and gonadotropins may be linked, impacting ovarian function. GH may benefit poor responders with GH deficiency, but its role in normal systems requires further investigation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Four-dimensional ultrasound guided embryo transfers improve live birth rates when compared to the clinical touch technique: a randomised controlled trial.

Scientific reports·2023

Same author

Evidence-based guideline: unexplained infertility†.

Human reproduction (Oxford, England)·2023

Same author

Retrospective Review of Acute Renal Colic Management in the Emergency Department and Review of Guidelines.

Urology practice·2023

Same author

Fertility Preservation in Female Patients with Cancer.

Clinical oncology (Royal College of Radiologists (Great Britain))·2022

Same author

Retrospective observational RT-PCR analyses on 688 babies born to 843 SARS-CoV-2 positive mothers, placental analyses and diagnostic analyses limitations suggest vertical transmission is possible.

Facts, views & vision in ObGyn·2021

Same author

Elective oocyte cryopreservation for age-related fertility decline.

Journal of assisted reproduction and genetics·2021

Area of Science:

Reproductive Endocrinology
Endocrinology
Molecular Biology

Background:

The reproductive and somatotrophic axes are increasingly recognized as interlinked.
The ovary is a target for growth hormone (GH) action, featuring a regulatory system of growth factors and binding proteins.
This intricate system fine-tunes gonadotropin action within the ovary.

Purpose of the Study:

To explore the clinical implications of the interlinked reproductive and somatotrophic axes.
To investigate the efficacy of cotreatment with growth hormone and gonadotropins, particularly in poor responders.
To understand the role of GH and growth factors in ovarian physiology and pathology.

Main Methods:

Clinical trials involving cotreatment with growth hormone and gonadotropins.
Analysis of treatment effects based on hormonal status and ovarian age.
Review of existing studies on GH and growth factor involvement in ovarian function.

Main Results:

Cotreatment with GH and gonadotropins has been trialed, primarily for poor responders to gonadotropin stimulation.
Treatment efficacy is contingent upon the patient's hormonal status and 'ovarian age'.
A potential role for supplementary GH has been identified in patients with GH deficiency, but not in those with normal GH levels.

Conclusions:

The interplay between GH and the reproductive axis is significant, particularly in ovarian response.
Further research is needed to clarify the benefits of GH and growth factors on follicle, oocyte, and endometrial function.
The potential role of GH and growth factors in polycystic ovary syndrome (PCOS) warrants continued investigation.

Related Experiment Videos