Related Experiment Videos
Scintigraphic findings in renal malakoplakia
1Department of Radiology, Bowman Gray School of Medicine, Winston-Salem, North Carolina 27157-1088, USA.
Clinical Nuclear Medicine
|June 1, 1995
Summary
This study presents a rare case of bilateral renal malakoplakia. Gallium-67 (Ga-67) scintigraphy showed increased activity in the kidneys, correlating with defects seen on technetium-99m gluceptate imaging.
Area of Science:
- Nuclear medicine
- Radiology
- Nephrology
Background:
- Renal malakoplakia is a rare chronic granulomatous disease affecting the kidneys.
- Diagnosis often relies on imaging and biopsy.
- Scintigraphy plays a role in evaluating renal function and pathology.
Observation:
- A rare case of bilateral renal malakoplakia was investigated.
- Gallium-67 (Ga-67) citrate scintigraphy was performed.
- Technetium-99m gluceptate (Tc-99m GH) and Indium-111 (In-111) leukocyte imaging were also utilized.
Findings:
- Ga-67 scintigraphy revealed markedly increased activity in both kidneys.
- These areas of increased Ga-67 uptake corresponded to focal cortical defects identified on Tc-99m GH imaging.
- No abnormal renal activity was observed with In-111 leukocyte scanning.
Implications:
- This case highlights the utility of Ga-67 scintigraphy in diagnosing renal malakoplakia.
- The findings suggest Ga-67 uptake may reflect active inflammation or specific cellular processes within the malakoplakic lesions.
- Discordance with In-111 leukocyte imaging warrants further investigation into the pathophysiology of renal malakoplakia.