[On the chemoreception mechanism of the ventrolateral medullary surface in rats]

This work is to investigate the mechanism of central chemoreception of the ventral medullary surface in respiratory regulation in rats. A series of methods including immunohistochemical (HRP), H+ permeation, microinjection, microiontophoresis, and destruction of related nuclei were used. Results showed that nucleus of trapezoid, lateroventral periolivary nucleus (LVPO), retrotrapezoid nucleus, lateral paragigantocellular nucleus and lateral reticular nucleus have the neural structural relations with the surface. Their processes or their soma might be receptive to the H+ applied to the ventral surface. It also demonstrated that both non-respiration related neuron (LVPO) and respiration related neuron (nucleus retrofacialis, NRF) might play roles in central chemoreception in respiratory regulation.