[Results of a quantitative study of the interaction of pathogenic enterobacteria with a cell monolayer]

A study was made of the cytopathic effect and dynamics of intracellular reproduction of S. typhimurium and shigellae in the monolayer of HeLa cells, macrophages (monocytes) of the peritoneal exudate of rabbits and rats and microphages (granulocytes) of the pleural exudate of rabbits. The presence of bactericidal mechanism in the host cell to the invaded infectious agent is postulated. An important role of the cell component of defence in insensibility in shigellosis is supposed.