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[Cytokines and hepatitis]
1Service d'hépatologie, hôpital Beaujon, Clichy.
Interferon is presently the treatment of chronic liver infection with hepatitis B and C viruses. Major advances have been made in the field of hepatitis B virus with interferon, which is able to clear viral replication in 30 to 40% of the cases. Interferon is also efficient in the treatment of hepatitis C chronic infections, normalizing transaminase activity in 60 to 70% of the patients, but a relapse is observed after interruption of treatment, and a sustained remission is obtained in only 20% of the cases. These results demonstrate the need for further clinical research to elucidate the precise indications of this treatment.
Interferon is presently the treatment of chronic liver infection with hepatitis B and C viruses. Major advances have been made in the field of hepatitis B virus with interferon, which is able to clear viral replication in 30 to 40% of the cases. Interferon is also efficient in the treatment of hepatitis C chronic infections, normalizing transaminase activity in 60 to 70% of the patients, but a relapse is observed after interruption of treatment, and a sustained remission is obtained in only 20% of the cases. These results demonstrate the need for further clinical research to elucidate the precise indications of this treatment.