Related Experiment Video
Updated: Aug 11, 2026

Generation of a Rat Model of Acute Liver Failure by Combining 70% Partial Hepatectomy and Acetaminophen
Published on: November 27, 2019
[The morphofunctional changes in the hepatocytes of rats with experimental acute pancreatitis]
Abstract:
Under experimental acute pancreatitis of rats, certain changes were revealed in the liver histological structure, hepatocyte population composition, intensity of hepatocyte DNA-synthesis, their proliferation, and in hepatocyte glycogen contents. These changes reflect a two-step process of hepatocyte activation. This results well compares with the earlier evidence on changes in pancreatic cell population under acute pancreatitis. The role of hepatocyte protective reactions during regenerative process in pancreas, under acute pancreatitis and its transition into chronic condition, is discussed.
More Related Videos
07:38Preparing a Mice Model of Severe Acute Pancreatitis via a Combination of Caerulein and Lipopolysaccharide Intraperitoneal Injection
Published on: May 10, 2024
03:07Development and Validation of a Methodology for Establishing Obese Rat Models with Typical Fatty Pancreas
Published on: November 11, 2025
Related Concept Videos
Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Acute Pancreatitis I: Introduction
Acute Pancreatitis II: Pathophysiology
Chronic Pancreatitis I: Introduction
Chronic Pancreatitis II: Pathophysiology