Related Experiment Video
Updated: Aug 19, 2026

An In Vitro Approach to Photodynamic Therapy
Published on: August 17, 2018
[Cutaneous carcinoma and papillomavirus 5. Discovered during prolonged UVA photochemotherapy]
P Bayle-Lebey1, F Labadie, N Basset-Seguin
1Service de Dermatologie, Hôpital Purpan, Toulouse.
Introduction:
HPV 5 is an opportunistic oncogenic virus found mainly in patients with verruciform epidermodysplasia or in certain immunodepressed patients.
Case:
We report the case of a 48-year-old patient who developed, over a 5 year period, 30 skin carcinomas after prolonged puvatreatment. HPV 5 was identified. The course has been stable under treatment with etretinate and alpha-interferon.
Comments:
The role of ultraviolet irradiation as a carcinogenic agent is raised by this observation, both as a primary factor and as a local factor favouring immunosuppression and proliferation of opportunistic HVP.
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