Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Validity testing of the accuPINCH THC test

A J Jenkins1, W D Darwin, M A Huestis

  • 1Addiction Research Center, NIDA/NIH, Baltimore, MD 21224.

Journal of Analytical Toxicology
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development and Characterisation of a Microneedle Sensor for Intrapartum Fetal Monitoring.

Biosensors·2025
Same author

Continuous subcutaneous insulin infusion: a local perspective.

Hong Kong medical journal = Xianggang yi xue za zhi·2023
Same author

Is perinatal substance abuse falling through the cracks?

Irish journal of psychological medicine·2023
Same author

Can Anti-Müllerian Hormone levels predict future pregnancy outcomes in recurrent pregnancy loss?

European journal of obstetrics, gynecology, and reproductive biology·2023
Same author

Substance use patterns in 9-10 year olds: Baseline findings from the adolescent brain cognitive development (ABCD) study.

Drug and alcohol dependence·2021
Same author

Biomarkers of Recent Cannabis Use in Blood, Oral Fluid and Breath.

Journal of analytical toxicology·2021

The accuPINCH THC test shows potential for rapid cannabinoid detection in urine. However, its accuracy varies, with positive results appearing at low concentrations and all concentrations for clinical samples.

Area of Science:

  • Forensic Toxicology
  • Analytical Chemistry

Background:

  • Self-contained drug-testing kits offer rapid results without laboratory needs.
  • Marketed kits aim for quick drug abuse screening.

Purpose of the Study:

  • To validate the accuPINCH THC test for detecting cannabinoids in urine.
  • To assess the test's performance against gas chromatography-mass spectrometry (GC-MS).

Main Methods:

  • A validity study involving three male volunteers smoking marijuana.
  • Urine samples analyzed blindly using accuPINCH and GC-MS for THCCOOH.
  • Assessed impact of turbidity, temperature, and reading time on test outcomes.

Main Results:

  • Positive B results correlated with THCCOOH concentrations >= 15 ng/mL.

Related Experiment Videos

  • Positive A and negative results occurred across all concentrations in clinical samples.
  • Drug-free samples were negative or positive A; low cross-reactivity observed.

    • Conclusions:

    • The accuPINCH THC test demonstrates variable performance in detecting THCCOOH.
    • Further validation is needed to establish reliable cut-off levels for accurate drug screening.