Related Experiment Videos
Urinary tract infections in children in a tertiary care service
1College of Medicine and Medical Sciences, King Faisal University, Dammam, Saudi Arabia.
Insights
Pediatric urinary tract infections (UTIs) often present with anomalies, particularly in infants. Common pathogens like E. coli show resistance to ampicillin and cotrimoxazole, necessitating careful antibiotic selection.
Area of Science:
- Pediatric Nephrology
- Infectious Diseases
- Urology
Background:
- Urinary tract infections (UTIs) are common in children, with varying associated anomalies and antibiotic sensitivities.
- Understanding these factors is crucial for effective management and improved patient outcomes.
Purpose of the Study:
- To investigate the characteristics of pediatric UTIs.
- To identify associated urinary tract anomalies.
- To determine antibiotic sensitivity patterns in children presenting with UTI.
Main Methods:
- Retrospective observational study conducted at King Fahd Hospital of the University-Al Khobar.
- Included infants and children up to 12 years with proven UTI (1988-1993).
- Investigations comprised plain X-rays, IVU, voiding cystourethrography, and abdominal ultrasound.
Main Results:
- 56% of patients were infants under 2 years; males predominated.
- Associated anomalies included hypospadias, hydronephrosis, prune-belly syndrome, and renal/anorectal anomalies.
- Escherichia coli, Klebsiella pneumoniae, and enterococci were the most common pathogens; ampicillin and cotrimoxazole showed low efficacy.
Conclusions:
- Findings highlight the importance of identifying associated anomalies in pediatric UTIs.
- Antibiotic resistance patterns necessitate a review of empirical treatment strategies.
- Therapeutic implications are critical for optimizing UTI management in children.
Objective:
To determine the nature of urinary tract infection (UTI), accompanying anomalies and antibiotic sensitivity in children in a tertiary care centre.
Design:
Retrospective observational study.
Setting:
King Fahd Hospital of the University-Al Khobar.
Subjects:
Infants and children with proven urinary tract infection (UTI). Age up to 12 years seen between 1988-1993. Investigations included plain xrays, IVU, voiding cystourethrography and ultrasound examination of the abdome.
Results:
40% of subjects were referred cases and for the other 60% it was the first contact. 56% were infants below 2 years, males were predominant and proportion of older children diminished with age. Prominent associated anomalies were hypospadias in the male (6.14%), hydronephrosis, prune-belly syndrome, renal parenchymal and anorectal anomalies. Organisms predominantly grown on culture were Escherichia coli, Klebsiella pneumoniae and enterococci. Ampicillin and cotrimoxazole were found to be least effective.
Conclusions:
Thereapeutic implications for the observations made are important to improve the outcome.