[A case of beneficial effect of ulinastatin on postoperative renal function in a patient with acute renal failure]

We experienced a case in which ulinastatin may have been beneficial to improve postoperative renal function in a patient with acute renal failure. The patient had acute renal failure with serum Cr of 9.3 mg.dl-1 after nephrectomy. On the 14th postoperative day, he underwent laparotomy under diagnosis of ileus. Administration of ulinastatin, 300,000 units.day-1 for 4 days, increased urine volume and creatine clearance and improved serum Cr level. This case suggests that ulinastatin might exert a beneficial effect on the recovery from renal tubular damage and on the glomerular filtration ratio, with resultant improvement of acute renal failure.