Vulvovaginal candidiasis: topical vs. oral therapy

Vulvovaginal candidiasis is extremely common. It may be treated with topical or oral antifungal medications. Topical therapy is efficacious and well-tolerated in most women. Oral therapy should be reserved for rare cases of severe and recalcitrant infection but should not be used in pregnant women, patients with diabetes or those using concomitant medications. An understanding of the pharmacotherapeutic characteristics of both oral and topical medications is a vital element in ensuring a favorable therapeutic outcome.