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[The hematological laboratory of clinical practice]
1Zentrallaboratorium, Kantonsspital Aarau.
Therapeutische Umschau. Revue Therapeutique
|May 1, 1995
Summary
Hematology lab tests, including blood cell counts and hemoglobin, require timely analysis for accuracy. Proper sample storage and recognition of minor pathological findings like fragmentocytes are crucial for patient diagnosis and quality control.
Area of Science:
- Hematology
- Clinical Pathology
- Laboratory Medicine
Context:
- Hematological laboratory analyses encompass erythrocyte, leukocyte, and platelet counts, hemoglobin concentration, hematocrit, red cell indices, and blood film examination.
- Timely analysis is critical: white blood cells, platelets, hematocrit, and MCV require determination within two hours of blood sampling.
- Sample integrity is maintained for five days for hemoglobin concentration, red-cell count, and MCH when stored at 4°C.
Purpose:
- To outline the essential parameters and analytical timelines in hematological laboratory testing.
- To emphasize the clinical significance of recognizing subtle morphological abnormalities in blood films.
- To highlight the importance of standardized grading and quality control in hematological diagnostics.
Summary:
- Key hematological parameters include cell counts, hemoglobin, hematocrit, and red cell indices, with specific time constraints for accurate determination.
- Microscopic examination of blood films is vital for identifying minor pathological findings, such as fragmentocytes in thrombotic-thrombocytopenic purpura.
- Standardized grading systems and robust quality assurance, including external controls, are essential for reliable hematological laboratory performance.
Impact:
- Ensures accurate and reliable diagnostic information from hematological tests.
- Improves the detection of critical, often subtle, pathological conditions.
- Upholds high standards in laboratory practice, contributing to effective patient care and management.