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Related Experiment Videos

Acquired QT interval changes and neck dissections

M A Acquadro1, T X Nghiem, T P Beach

  • 1Department of Anesthesia, Massachusetts Eye and Ear Infirmary, Boston 02114, USA.

Journal of Clinical Anesthesia
|February 1, 1995
PubMed
Summary

Acquired long QT syndrome after neck dissection is unlikely to cause malignant arrhythmias or death. This study found no fatal events in patients undergoing radical or modified neck dissections.

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Area of Science:

  • Cardiology
  • Otolaryngology
  • Oncology

Background:

  • Radical neck dissection can potentially affect cardiac function.
  • Long QT syndrome is a known risk factor for arrhythmias.

Purpose of the Study:

  • To investigate the occurrence of malignant arrhythmias and deaths in patients with acquired long QT syndrome following neck dissections.
  • To assess the cardiac safety of radical and modified neck dissections.

Main Methods:

  • Prospective study involving 69 patients undergoing extensive neck surgery.
  • Patients were monitored for QT intervals and arrhythmias preoperatively and postoperatively.
  • Analysis compared QTc intervals among groups undergoing right radical, left radical, or no radical neck dissection.

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Main Results:

  • 38 patients developed a corrected QT (QTc) interval > 440 milliseconds postoperatively.
  • A statistically significant change in QTc was observed from preoperative to postoperative periods.
  • No malignant arrhythmias or deaths were recorded in any patient group.

Conclusions:

  • Acquired long QT syndrome following neck dissection, in the absence of congenital, metabolic, or pharmacologic factors, does not appear to trigger malignant arrhythmias.
  • The risk of fatal arrhythmias after radical neck dissection may be lower than previously suggested.