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Updated: Aug 26, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Three cases of organoid nevus on the trunk and extremity
T Kanekura1, M Kawahira, T Kanzaki
1Department of Dermatology, Faculty of Medicine, Kagoshima University, Japan.
Abstract:
Organoid nevi are most commonly observed on the scalp. Although they are rarely found on the trunk and extremities, we were able to study 3 cases of organoid nevi involving distributions of this sort. These included a 39-year-old male with a 2 x 6 cm brown area on the left flank (case 1), an 8-year-old female with a 5 x 6 cm hypopigmented macule on the lower left leg (case 2), and a 45-year-old male with a 1.5 x 3 cm brown spot on the back (case 3). All these were histopathologically confirmed to be organoid nevi. The lesion in case 1 revealed basal cell epithelioma, that in case 2 exhibited hypohidrosis caused by poorly developed sweat glands, and the lesion in case 3 was typical, as was an additional one on the same patient's scalp.
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