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Biometry in X linked megalocornea: pathognomonic findings
1University Hospital Ghent, Department of Pediatric Ophthalmology, Belgium.
The British Journal of Ophthalmology
|October 1, 1994
Summary
This study on 11 males found deep anterior chamber depth and short vitreous length in affected eyes. These biometric findings aid in diagnosing infantile glaucoma and megalocornea.
Area of Science:
- Ophthalmology
- Medical Biometrics
Background:
- Primary infantile glaucoma and megalocornea present with enlarged corneas.
- Accurate biometric measurements are crucial for diagnosis.
Purpose of the Study:
- To characterize the biometric findings in affected males.
- To evaluate the utility of postlimbal depth in assessing ocular structures.
- To differentiate between primary infantile glaucoma and megalocornea.
Main Methods:
- Biometric study of 11 affected males.
- Measurement of corneal radius, anterior chamber depth (AC depth), and vitreous length.
- Calculation of postlimbal depth to determine iris and lens position.
Main Results:
- Patients exhibited large corneas with short radii.
- Significantly deep AC depth (exceeding +2 SD) and short vitreous length were observed.
- Posterior positioning of the iris and lens was identified, occurring at the expense of vitreous volume.
Conclusions:
- Distinct biometric parameters characterize affected individuals.
- Postlimbal depth analysis provides insights into ocular structure positioning.
- Biometric data are vital for diagnosing and differentiating infantile glaucoma and megalocornea.