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Updated: Aug 14, 2026

DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat (VNTR) - Fragment Length Analysis (FLA)
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Leprosy

V N Sehgal1

  • 1Department of Dermatology and Venereology, University College of Medical Sciences, Delhi, India.

Dermatologic Clinics
|October 1, 1994
PubMed

Insights

Leprosy, a chronic infectious disease caused by Mycobacterium leprae, is reviewed. This article covers its epidemiology, causes, classification, symptoms, reactions, diagnosis, and treatment.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Public Health

Background:

  • Leprosy is a chronic infectious disorder.
  • Mycobacterium leprae is the presumed causative agent.
  • Understanding leprosy is crucial for public health initiatives.

Purpose of the Study:

  • To provide a comprehensive review of leprosy.
  • To cover key aspects including epidemiology, pathogenesis, and clinical presentation.
  • To outline current diagnostic and treatment strategies.

Main Methods:

  • Literature review of scientific articles and clinical studies.
  • Synthesis of information on leprosy's multifaceted aspects.
  • Analysis of epidemiological data and treatment outcomes.

Main Results:

  • Detailed overview of leprosy epidemiology worldwide.
  • Explanation of Mycobacterium leprae's role in disease development.
  • Comprehensive description of clinical manifestations and leprosy reactions.
  • Summary of diagnostic methods and recommended treatments.

Conclusions:

  • Leprosy remains a significant global health concern.
  • Effective management requires understanding its complex epidemiology and pathogenesis.
  • Current diagnostic and treatment protocols aim to reduce disease burden and transmission.

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