Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Immunoliposomes in vivo

M H Vingerhoeds1, G Storm, D J Crommelin

  • 1Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, The Netherlands.

Immunomethods
|June 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Local delivery of lipid-based nanoparticles containing microbial nucleic acid for osteoimmunomodulation.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences·2025
Same author

Nanobody-liposomes as novel cancer vaccine platform to efficiently stimulate T cell immunity.

International journal of pharmaceutics·2024
Same author

Osteoimmunomodulatory GelMA/liposome coatings to promote bone regeneration of orthopedic implants.

Journal of controlled release : official journal of the Controlled Release Society·2023
Same author

Liposome induction of CD8<sup>+</sup> T cell responses depends on CD169<sup>+</sup> macrophages and Batf3-dependent dendritic cells and is enhanced by GM3 inclusion.

Journal of controlled release : official journal of the Controlled Release Society·2021
Same author

Port wine stain treatment outcomes have not improved over the past three decades.

Journal of the European Academy of Dermatology and Venereology : JEADV·2019
Same author

A technical protocol for an experimental ex vivo model using arterially perfused porcine eyes.

Experimental eye research·2019
Same journal

Generation of Human Monoclonal Autoantibody-Producing Cell Lines by Epstein-Barr Virus Transformation of Autoreactive B Lymphocytes and by Somatic Cell Hybridization Techniques: Application to the Analysis of the Autoimmune B Cell Repertoire.

ImmunoMethods·2016
Same journal

Immunologically based methods for the elimination of tumor cells from autologous stem cell grafts.

ImmunoMethods·1994
Same journal

Detection of minimal residual disease in autologous grafts.

ImmunoMethods·1994
Same journal

Peripheral blood progenitor cell transplantation for hematological malignancies.

ImmunoMethods·1994
Same journal

Genetic marking and manipulation of hematopoietic progenitor cells using retroviral vectors.

ImmunoMethods·1994
Same journal

T-cell depletion and manipulation in allogeneic hematopoietic cell transplantation.

ImmunoMethods·1994
See all related articles

Antibodies attached to liposomes create immunoliposomes for targeted drug delivery. This review covers in vivo studies, challenges, and therapeutic potential of this drug targeting system.

Area of Science:

  • Biotechnology
  • Nanomedicine
  • Immunology

Background:

  • Liposomes are lipid vesicles used for drug delivery.
  • Antibody attachment confers specificity to target cells or organs.
  • Immunoliposomes are designed as targeted drug carriers.

Purpose of the Study:

  • To review in vivo studies on immunoliposome targeting.
  • To describe anatomical, physiological, and pathological constraints.
  • To discuss the therapeutic feasibility of immunoliposome drug targeting.

Main Methods:

  • Literature review of in vivo studies.
  • Analysis of targeting efficiency and biodistribution.
  • Evaluation of anatomical and physiological barriers.

Related Experiment Videos

Main Results:

  • Immunoliposomes show potential for targeted drug delivery in vivo.
  • Various factors influence targeting efficiency, including antibody affinity and liposome characteristics.
  • Challenges remain in achieving specific and efficient targeting in complex biological systems.

Conclusions:

  • Immunoliposomes represent a promising drug targeting system.
  • Further research is needed to overcome existing constraints for therapeutic application.
  • Optimizing immunoliposome design and understanding in vivo behavior are crucial for clinical success.