[Biological characteristics of salmonellae isolated from different clinical disease forms]

The same types of salmonellae with the same antigenic structure could be the causative agents of various clinical forms of diseases. Two groups of strains of 11 serological types isolated from the patients were studied on 4 biological models: in the keratoconjunctival test on guinea pigs, on a pulmonary model, on an isolated loop of the rabbit intestine and on chick embryos. Results demonstrated that the form of the disease could be a reflection not only of the state of the macroorganism reactivity, but also of the characteristics of the strain of the causative agent. Thus, of 23 strains isolated from the patients with dysentery-like and typhoid form of salmonellosis, 6 caused keratoconjunctivitis and demonstrated a high virulence on all the models in comparison with the 22 strains isolated from patients with the gastrointestinal form.