Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

D-901 neonatal oxygenator: a new perspective

F De Somer1, K François, L Foubert

  • 1Department of Perfusion, University Hospital Gent, Belgium.

Perfusion
|January 1, 1994
PubMed
Summary

The D-901 neonatal oxygenator effectively reduced prime volume and homologous blood use in infant cardiac surgery. This device offers promising perfusion for neonates, maintaining good gas transfer with no device-related issues.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rational thresholding of circulating tumor DNA concentration for improved surveillance of metastatic breast cancer.

ESMO open·2024
Same author

Evaluation of the use of a heparin dose-response test in dogs to determine the optimal heparin dose during intravascular procedures and assessment of the in vitro heparin response in healthy dogs.

Veterinary medicine and science·2023
Same author

Surgical correction of an infundibular pulmonic stenosis and ventricular septal defect in a Shetland Sheepdog.

Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology·2023
Same author

Computed tomography confirmation of an interluminal connection in the Rüsch EZ-blocker™.

Anaesthesia reports·2023
Same author

Tuberculosis and pseudoaneurysms.

Medecine et maladies infectieuses·2020
Same author

Use of a right ventricular continuous flow pump to validate the distensible model of the pulmonary vasculature.

Physiological research·2019

Area of Science:

  • Biomedical Engineering
  • Pediatric Cardiology
  • Cardiovascular Surgery

Background:

  • Congenital heart disease necessitates cardiopulmonary bypass in infants.
  • Neonatal perfusion requires specialized oxygenators to manage small blood volumes and minimize complications.

Purpose of the Study:

  • To evaluate the D-901 neonatal oxygenator for infant cardiac surgery.
  • To assess its priming volume, blood handling, and gas transfer capabilities.
  • To determine its impact on homologous blood product usage.

Main Methods:

  • Five infants with congenital heart disease underwent cardiac surgery using the D-901 oxygenator.
  • Prime volume was compared to patient blood volume.
  • Gas transfer (oxygen and carbon dioxide) and blood parameters (platelets, free hemoglobin) were monitored.

Related Experiment Videos

Main Results:

  • Prime volume was less than or equal to patient blood volume, reducing homologous blood use.
  • Achieved a prime volume of 220 ml with adaptable tubing.
  • Demonstrated maximum oxygen transfer of 45 ml/min and CO2 removal of 50 ml/min.
  • Mean platelet count decreased to 91% of baseline; mean free hemoglobin increased to 86 mg/100 ml at 120 minutes.

Conclusions:

  • The D-901 oxygenator presents new possibilities for neonatal perfusion regarding priming volume and blood product use.
  • It maintains adequate gas transfer characteristics for small infants.
  • Further studies with larger patient cohorts are needed to fully establish its capabilities and limitations.