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[Cyclocryotherapy for refractory glaucoma after penetrating keratoplasty]
1Zhongshan Opthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou, China.
Yan Ke Xue Bao = Eye Science
|June 1, 1994
Summary
Cyclocryotherapy effectively controls intraocular pressure in secondary glaucoma patients post-keratoplasty. Precise cryotherapy application and post-operative care are crucial for successful outcomes and visual function preservation.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Corneal Surgery
Context:
- Secondary glaucoma following penetrating keratoplasty presents a significant clinical challenge.
- Patients often exhibit resistance to conventional anti-glaucoma medications and standard filtering procedures.
- Evaluating alternative therapeutic modalities is essential for managing refractory glaucoma post-keratoplasty.
Purpose:
- To assess the efficacy and safety of cyclocryotherapy using nitrogen monoxide in patients with secondary glaucoma after penetrating keratoplasty.
- To determine the long-term outcomes regarding intraocular pressure control, graft clarity, and visual function preservation.
Summary:
- Twenty-eight patients (28 eyes) with refractory secondary glaucoma post-penetrating keratoplasty underwent cyclocryotherapy.
- Follow-up exceeding one year demonstrated successful intraocular pressure control in 89% of eyes.
- Graft clarity was maintained in 85% of eyes, and visual functions were preserved in 82% of patients.
Impact:
- This study highlights cyclocryotherapy as a viable treatment option for refractory secondary glaucoma post-keratoplasty.
- Precise control of cryotherapy parameters (temperature, time, extent) and judicious use of post-operative anti-rejection agents are identified as critical success factors.
- Avoiding both over-treatment (to prevent ocular atrophy) and under-treatment (in the initial procedure) is emphasized for optimal patient outcomes.