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[Localized Sweet syndrome]

B Brechtel1, N Haas, B M Czarnetzki

  • 1Universitätsklinikum Rudolf Virchow, Freie Universität Berlin.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|December 1, 1994
PubMed
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This case study presents a rare localized form of Sweet's syndrome, an inflammatory skin condition, presenting as a large cheek tumor. Prompt systemic corticosteroid treatment led to rapid regression without scarring.

Area of Science:

  • Dermatology
  • Pathology

Background:

  • Sweet's syndrome, also known as acute febrile neutrophilic dermatosis, is a rare inflammatory condition.
  • It is characterized by sudden onset of fever, neutrophilia, and tender, erythematous papules and plaques.

Observation:

  • A 73-year-old woman presented with a rapidly developing inflammatory tumor on her right cheek.
  • The lesion, over 7 cm in diameter, featured a central crater and sterile pustules.
  • Histology revealed dense dermal neutrophil infiltration without vasculitis or tissue destruction.

Findings:

  • The patient had recurrent chronic bronchitis but no fever or leukocytosis.
  • Antibiotic treatment was ineffective, but systemic high-dose corticosteroids resulted in rapid tumor regression and complete resolution without scarring.

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  • The case met major and minor criteria for Sweet's syndrome, indicating a rare localized presentation.

    • Implications:

    • This case highlights a rare localized variant of Sweet's syndrome.
    • It underscores the importance of considering Sweet's syndrome in inflammatory facial tumors, even without typical systemic symptoms.
    • Effective management with systemic corticosteroids suggests their utility in such unusual presentations.