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Sympathetic skin response

J A Gutrecht1

  • 1Department of Neurology, Lahey Clinic, Burlington, Massachusetts 01805.

Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society
|September 1, 1994
PubMed
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The sympathetic skin response (SSR) measures sweat gland activity to assess peripheral and central nervous system disorders. This review details SSR

Area of Science:

  • Neuroscience
  • Autonomic Nervous System Function
  • Electrophysiology

Background:

  • The sympathetic skin response (SSR) is a neurophysiological potential generated by sweat gland activity.
  • It reflects the function of the sympathetic nervous system and is used in clinical assessments.

Purpose of the Study:

  • To provide a comprehensive review of the sympathetic skin response (SSR).
  • To outline its history, physiopathogenesis, analysis, and study techniques.
  • To present its association with peripheral and central nervous system diseases.

Main Methods:

  • Review of historical data and scientific literature on SSR.
  • Description of electrophysiological techniques for SSR measurement.
  • Analysis of SSR characteristics like habituation and latency.

Related Experiment Videos

Main Results:

  • SSR latency varies between the hand (1.3-1.5 s) and foot (1.9-2.1 s).
  • SSR habituates with closely repeated stimuli.
  • The response is often absent in peripheral neuropathy, particularly with autonomic symptoms.

Conclusions:

  • SSR is a valuable tool for studying the peripheral sympathetic system in diseases like neuropathy.
  • SSR can also provide insights into central sympathetic nervous system disorders.
  • Understanding SSR's characteristics is crucial for accurate clinical interpretation.