Related Experiment Videos
Septal short atrioventricular delay pacing: additional hemodynamic improvements in heart failure
R Cowell1, J Morris-Thurgood, C Ilsley
1Cardiology Department, Harefield Hospital, Middlesex, United Kingdom.
Pacing and Clinical Electrophysiology : PACE
|November 1, 1994
Summary
Short AV delay pacing can benefit patients with left ventricular dysfunction. Septal pacing significantly improves cardiac output compared to apical pacing in heart failure patients.
Area of Science:
- Cardiology
- Medical Devices
Background:
- Short AV delay pacing is debated for left ventricular dysfunction.
- Right ventricular apical pacing may cause asynchronous contractions, limiting benefits.
Purpose of the Study:
- To compare hemodynamic effects of septal versus apical right ventricular pacing in heart failure patients.
- To evaluate VDD pacing with short AV delays (50, 100, 150 msec).
Main Methods:
- Compared septal and apical right ventricular activation in 15 heart failure patients.
- Utilized VDD pacing with varying AV delays.
Main Results:
- Apical VDD pacing showed no significant cardiac output increase (4.1 to 4.45 L/min).
- Septal VDD pacing significantly increased cardiac output (4.1 to 4.86 L/min, P=0.037).
- Septal pacing improved cardiac output in 11 patients, apical in 10.
Conclusions:
- Selected patients with ventricular dysfunction benefit from short AV delay pacing.
- Septal ventricular activation offers significant hemodynamic advantages over apical activation.