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Fluorescent location of malignant cells in smears obtained from sputum
F S Steven1, P W Payne, B Palcic
1Department of Biochemistry and Molecular Biology, School of Bioloical Sciences, University of Manchester, UK.
Anticancer Research
|September 1, 1994
Abstract:
A fluorescent probe (rhodamine a-N-agmatine) has been used to locate cells possessing a surface protease in sputum smears. Malignant epithelial cells possess this protease and can be quickly located by this technique. These results have been confirmed by using a second fluorescent probe (9-animo acridine) for this same cell surface protease.