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[Theoretical analysis about an optimal screening interval for renal cell carcinoma]
N Fujimoto1, A Sugita, Y Terasawa
1Department of Urology, University of Occupational and Environmental Health.
Nihon Hinyokika Gakkai Zasshi. the Japanese Journal of Urology
|December 1, 1994
Summary
Ultrasonography can detect most small renal cell carcinomas (RCC) if screening occurs every three years for individuals over 40. This study found slow tumor growth, with doubling times averaging 468 days.
Area of Science:
- Urology
- Oncology
- Radiology
Background:
- Increasing incidence of incidentally detected renal cell carcinoma (RCC).
- Ultrasonography is a key tool for early RCC detection.
- Optimal screening intervals for ultrasonography remain undetermined.
Purpose of the Study:
- To investigate the growth rate of renal cell carcinoma (RCC) in untreated patients.
- To determine optimal ultrasonography screening intervals for early RCC detection.
Main Methods:
- Observation of tumor growth in 6 patients with incidentally detected RCC.
- Calculation of tumor volume doubling time.
Main Results:
- Renal cell carcinoma (RCC) demonstrated slow growth.
- Tumor volume doubling time ranged from 372 to 579 days (mean 468 +/- 84.6 days).
Conclusions:
- Screening with ultrasonography every 3 years can detect most renal cell carcinomas (RCC) between 1.5 and 3 cm.
- Screening should be considered for individuals over 40 years of age.