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The effect of actinomycin D on the megakaryocytic line in rat
1Institute of Histology and Embryology, 3rd Medical Faculty, Charles University, Praha, Czech Republic.
Abstract:
Four-day administration of actinomycin D to the albino rat in daily doses of 25 micrograms/kg decreased--in relation to all blood cells of the bone marrow--the values of the more mature stages of the megakaryocytic line, i.e. megakaryocytes and naked megakaryocyte nuclei. The number of megakaryoblasts was not influenced.

