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Pemphigoid nodularis: a report of two cases
J F Bourke1, J Berth-Jones, D J Gawkrodger
1Department of Dermatology, Leicester Royal Infirmary, UK.
Clinical and Experimental Dermatology
|November 1, 1994
Summary
Pemphigoid nodularis, a rare bullous pemphigoid variant, presents as itchy, thickened nodules that can appear years before blisters. This often treatment-resistant condition is more common in females.
Area of Science:
- Dermatology
- Autoimmune blistering diseases
Background:
- Pemphigoid nodularis is a rare clinical variant of bullous pemphigoid.
- It is characterized by pruritic, hyperkeratotic nodules.
Observation:
- Nodules can be the initial presentation, preceding blister formation by years.
- The condition shows a higher prevalence in females.
- Pemphigoid nodularis is frequently resistant to standard treatments.
Findings:
- This report details two confirmed and one possible case of pemphigoid nodularis.
- A review of existing literature on this rare disorder is included.
Implications:
- Understanding pemphigoid nodularis aids in early diagnosis and management of this rare condition.
- Further research may elucidate optimal treatment strategies for this resistant disorder.