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[Increase of nonspecific resistance of the body in normal pregnancy]
The phagocytic function of blood neutrophils, hemolytic activity of the complement, levels of blood serum total IgG and of IgG-containing circulating immune complexes (CIC) were studied in 87 somatically healthy nonpregnant and pregnant women. A normal course of pregnancy was found to be associated with a marked increase of neutrophilic absorption capacity and bactericidal potential, as well as with increased activity of the complement. Despite a decrease of the concentration of total IgG in the IInd and IIIrd gestation trimesters, the level of IgG-containing CIC was unreliably, though constantly increased over the entire course of pregnancy, in comparison with that in nonpregnant women. Hence, stimulation of nonspecific resistance of the body permits pregnant women cope with the antigenic loading of a fetal origin.
The phagocytic function of blood neutrophils, hemolytic activity of the complement, levels of blood serum total IgG and of IgG-containing circulating immune complexes (CIC) were studied in 87 somatically healthy nonpregnant and pregnant women. A normal course of pregnancy was found to be associated with a marked increase of neutrophilic absorption capacity and bactericidal potential, as well as with increased activity of the complement. Despite a decrease of the concentration of total IgG in the IInd and IIIrd gestation trimesters, the level of IgG-containing CIC was unreliably, though constantly increased over the entire course of pregnancy, in comparison with that in nonpregnant women. Hence, stimulation of nonspecific resistance of the body permits pregnant women cope with the antigenic loading of a fetal origin.