[Use of a mathematical model to establish normal serum parameters characterizing the function of the fetoplacental complex]

Based on the author, data on the content of alpha-fetoprotein, trophoblastic beta-1-glycoprotein, and nonconjugated estriol in the blood serum of 278 somatically healthy women in various periods of normal gestation, the author proposes an approach to the definition of normal range of values. Using mathematical simulation methods, the values of normal concentrations of the fetoplacental complex products were calculated for every week of gestation, this permitting a different representation of laboratory findings and a dynamic follow-up of the course of gestation.