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Sedatives, tranquilizers, and stimulants

T M Dyke1

  • 1Department of Veterinary Clinical Sciences, Ohio State University College of Veterinary Medicine, Columbus.

The Veterinary Clinics of North America. Equine Practice
|December 1, 1993
PubMed
Summary
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This review covers central nervous system (CNS) depressant and stimulant drugs used in equine practice, detailing their mechanisms, uses, and side effects. Understanding these CNS-modifying drugs

Area of Science:

  • Veterinary Pharmacology
  • Equine Medicine
  • Central Nervous System (CNS) Therapeutics

Background:

  • Central nervous system (CNS) modifying drugs are integral to equine practice.
  • These drugs are broadly categorized into depressants and stimulants.
  • Understanding their effects is crucial for safe and effective equine care.

Purpose of the Study:

  • To review the pharmacologic mechanisms of action for selected CNS depressant and stimulant drugs in horses.
  • To outline the clinical uses of these CNS-modifying agents in equine practice.
  • To discuss the potential side effects associated with their administration.

Main Methods:

  • Literature review of pharmacologic and clinical studies on CNS drugs in horses.
  • Classification of drugs based on their primary effect on the CNS (depressant or stimulant).

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  • Analysis of available data on drug mechanisms, therapeutic applications, and adverse events.

    • Main Results:

    • Selected CNS depressant drugs include sedatives, hypnotics, and anesthetics, each with distinct mechanisms and uses.
    • Selected CNS stimulant drugs encompass psychostimulants and analeptics, with varying applications.
    • Limited data exists regarding the impact of these CNS-modifying drugs on equine performance.

    Conclusions:

    • A comprehensive understanding of CNS depressant and stimulant drug pharmacology is essential for equine veterinarians.
    • Careful consideration of drug mechanisms, uses, and side effects is necessary for optimal patient outcomes.
    • Further research is warranted to elucidate the effects of these drugs on equine performance.