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[Causal agents of onychomycosis]
G E Canteros1, G O Davel, W Vivot
1Instituto Nacional de Microbiología Dr. Carlos G. Malbrán, Buenos Aires, Argentina.
Revista Argentina De Microbiologia
|April 1, 1994
Summary
Onychomycosis, a fungal nail infection, is more common in women and individuals aged 30-70. Dermatophytes and yeasts are the primary causes, with specific species varying between toenail and fingernail infections.
Area of Science:
- Medical Mycology
- Dermatology
- Infectious Diseases
Context:
- Onychomycosis is a common nail infection with significant clinical implications.
- Understanding the etiological agents is crucial for effective treatment strategies.
- Previous studies have varied in their reported frequencies of fungal isolates.
Purpose:
- To determine the frequency of fungal species causing onychomycosis in a cohort of immunocompetent patients.
- To analyze the distribution of causative agents in toenail versus fingernail infections.
- To identify demographic patterns associated with onychomycosis.
Summary:
- A review of 307 specimens revealed that 68% were positive for fungal elements.
- Dermatophytes (60%) and yeasts (39%) were the predominant fungal groups identified.
- Trichophyton rubrum was the most common dermatophyte in toenails, while Candida albicans predominated in fingernails.
Impact:
- This study provides valuable epidemiological data on fungal nail infections.
- Findings can inform clinical diagnosis and antifungal prescribing practices.
- Highlights the importance of differentiating between toenail and fingernail onychomycosis for targeted therapy.