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Lacrimal sac tumors
M A Stefanyszyn1, A A Hidayat, J J Pe'er
1Wills Eye Hospital, Philadelphia, Pennsylvania.
Ophthalmic Plastic and Reconstructive Surgery
|September 1, 1994
Summary
Lacrimal sac tumors are often malignant (55% rate), presenting with epiphora or masses. Complete surgical excision of the tumor and drainage system, with radiation, is crucial for treating these aggressive epithelial malignancies.
Area of Science:
- Ophthalmology
- Pathology
- Oncology
Background:
- Lacrimal sac neoplasms are rare but can be aggressive.
- Understanding the clinicopathologic features is vital for diagnosis and treatment.
Purpose of the Study:
- To analyze the clinicopathologic characteristics of 115 lacrimal sac neoplasms.
- To determine the malignancy rate and identify prognostic factors.
Main Methods:
- Clinicopathologic review of 115 adult lacrimal sac tumors.
- Classification into epithelial and nonepithelial types.
- Literature review for comparative analysis.
Main Results:
- A 55% malignancy rate was observed.
- Epithelial tumors were more common (82 cases) than nonepithelial (33 cases).
- Squamous cell carcinoma was the most frequent malignant epithelial neoplasm.
Conclusions:
- Lacrimal sac tumors have a high malignancy rate.
- Aggressive epithelial malignancies require extensive surgical resection and adjuvant therapy.
- Early diagnosis and comprehensive treatment are essential for improved outcomes.