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Updated: Aug 12, 2026

A Comprehensive Protocol for Manual Segmentation of the Medial Temporal Lobe Structures
Published on: July 2, 2014
A temporal-abstraction mediator for protocol-based decision-support systems
1Section on Medical Informatics, Stanford University School of Medicine, California 94305-5479.
Abstract:
The inability of many clinical decision-support applications to integrate with existing databases limits the wide-scale deployment of such systems. To overcome this obstacle, we have designed a data-interpretation module that can be embedded in a general architecture for protocol-based reasoning and that can support the fundamental task of detecting temporal abstractions. We have developed this software module by coupling two existing systems--RESUME and Chronus--that provide complementary temporal-abstraction techniques at the application and the database levels, respectively. Their encapsulation into a single module thus can resolve the temporal queries of protocol planners with the domain-specific knowledge needed for the temporal-abstraction task and with primary time-stamped data stored in autonomous clinical databases. We show that other computer methods for the detection of temporal abstractions do not scale up to the data- and knowledge-intensive environments of protocol-based decision-support systems.
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