Primary corneal epithelial dysplasia (corneal intraepithelial neoplasia)

A 49 year-old man consulted in March 1980 for pain, eyestrain and decreased vision at the right eye. He presented a slightly elevated and transparent lesion, strictly limited to the corneal epithelium and treated with eyedrops until November 1980. The patient was seen again 12 years later in October 1992 with still the same complaints and a practically unchanged corneal lesion. The diagnosis of primary corneal epithelial dysplasia (Corneal Intraepithelial Neoplasia-Corin) was made and the abnormal epithelium completely removed under local anesthesia. After the operation the cornea became normal again and the patient free of complaints. The authors discuss the clinical symptoms, pathology, pathogeny and treatment of primary corneal epithelial dysplasia (Corneal Intraepithelial Neoplasia-Corin).