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Rectal malacoplakia in renal transplantation: MR features
M F Bellin1, M A Darchen, C Hoang
1Department of Radiology, Hôpital Pitié Salpétrière, Paris, France.
Journal of Computer Assisted Tomography
|November 1, 1994
Summary
This study details the CT and MRI imaging characteristics of rectal malacoplakia in a renal transplant patient. These findings help differentiate this rare condition from other rectal lesions using imaging features.
Area of Science:
- Radiology
- Gastroenterology
- Immunology
Background:
- Rectal malacoplakia is a rare chronic granulomatous disease.
- Renal transplant recipients are at increased risk due to immunosuppression.
Observation:
- A case of rectal malacoplakia in a renal transplant recipient is presented.
- The lesion exhibited specific features on computed tomography (CT) and magnetic resonance (MR) imaging.
Findings:
- On unenhanced CT, the lesion was strongly hyperdense (105 HU).
- On MR imaging, it showed hypointense signals on T1- and T2-weighted sequences with slight homogeneous enhancement post-gadolinium.
- These imaging findings are distinct from typical neoplastic or inflammatory rectal lesions.
Implications:
- Understanding these imaging features aids in differentiating rectal malacoplakia from other rectal pathologies.
- Characteristic intracytoplasmic siderocalcific spherules contribute to the suggestive imaging findings on CT and MRI.
- Accurate diagnosis can guide appropriate clinical management for patients, particularly immunocompromised individuals.