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Updated: Jul 26, 2026

07:31
Injection of Syngeneic Murine Melanoma Cells to Determine Their Metastatic Potential in the Lungs
Published on: May 24, 2016
Metastatic malignant melanoma: an unusual case presentation
J A Cunningham1, J P Fendler, P J Nichols
1Department of Urology, Kenneth Norris Jr. Cancer Hospital, Los Angeles, California.
Urology
|December 1, 1994
Summary
Metastatic melanoma rarely causes urinary symptoms but can present as a renal mass and hematuria. This rare presentation of metastatic melanoma to the kidney should be considered in clinical diagnoses.
Area of Science:
- Oncology
- Nephrology
- Urology
Background:
- Malignant melanoma commonly metastasizes to the genitourinary tract, but this is typically an incidental autopsy finding.
- Clinical presentation of genitourinary melanoma metastasis is infrequent, posing diagnostic challenges.
Observation:
- A previously asymptomatic patient presented with gross hematuria, a concerning urinary symptom.
- Imaging revealed a large renal mass, prompting further investigation.
Findings:
- The renal mass was diagnosed as metastatic melanoma.
- This case highlights a rare clinical manifestation of advanced melanoma.
Implications:
- Metastatic melanoma to the kidney should be included in the differential diagnosis for patients presenting with hematuria.
- Early consideration of rare metastatic sites can improve diagnostic accuracy and patient outcomes.
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