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[Propofol in general anesthesia in children]

M Cvejanov1, L Pejakov, S Marinković

  • 1Institut za zdravstvenu zastitu dece i omladine, Medicinski fakultet, Novi Sad.

Medicinski Pregled
|January 1, 1993
PubMed

Insights

Propofol anesthesia in children showed a faster recovery than barbiturate anesthesia, making it suitable for day care centers. However, it caused more cardiovascular changes and side effects during induction.

Area of Science:

  • Anesthesiology
  • Pediatric Medicine

Context:

  • Propofol is widely used for adult total intravenous anesthesia.
  • Limited data exists on propofol's use in pediatric anesthesia.

Purpose:

  • To compare propofol anesthesia with barbiturate (thiopentone and halothane) anesthesia in children.
  • Evaluate effects on induction, maintenance, and recovery.

Summary:

  • 50 children received propofol (average dose 2.38 mg/kg), compared to 50 in the control group (thiopentone/halothane).
  • Propofol group experienced greater decreases in systolic and diastolic pressure during induction, which stabilized later.
  • Propofol anesthesia had more side effects (pain, apnea, movements) than halothane anesthesia.

Impact:

  • Propofol anesthesia resulted in a shorter recovery period.
  • This suggests propofol's advantage for pediatric anesthesia in day care settings.

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