Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Abnormal microvascular responses in a lateral epicondylitis

R W Smith¹, E Papadopolous, R Mani

¹Department of Rheumatology, Southampton University Hospital.

British Journal of Rheumatology

|December 1, 1994

Summary

Patients with lateral epicondylitis showed an absent sympathetic vasomotor response (SVR) in affected skin. This suggests sympathetic nervous system dysfunction may contribute to epicondylitis pain.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Effectiveness of brainwave entrainment on pre-operative fear and anxiety in pediatric dental patients: a randomized controlled trial.

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry·2024

Same author

The diabetes community exercise programme plus usual care versus usual care in patients with type 2 diabetes: A randomised, two-arm, parallel, open-label trial.

EClinicalMedicine·2022

Same author

A biopsychosocial understanding of lower back pain: Content analysis of online information.

European journal of pain (London, England)·2017

Same author

A rare case of bullhorn-injury associated traumatic hernia of anterior abdominal wall managed by laparoscopic sutured tissue-only repair.

Journal of postgraduate medicine·2017

Same author

Search for new phenomena in events containing a same-flavour opposite-sign dilepton pair, jets, and large missing transverse momentum in [Formula: see text] [Formula: see text][Formula: see text] collisions with the ATLAS detector.

The European physical journal. C, Particles and fields·2017

Same author

Electron efficiency measurements with the ATLAS detector using 2012 LHC proton-proton collision data.

The European physical journal. C, Particles and fields·2017

Area of Science:

Orthopedics
Vascular Biology
Neuroscience

Background:

Lateral epicondylitis, commonly known as tennis elbow, is a painful condition affecting the tendons of the forearm.
The role of the sympathetic nervous system in localized pain conditions like epicondylitis is not fully understood.
Microvascular blood flow regulation is crucial for tissue health and pain perception.

Purpose of the Study:

To investigate the sympathetic vasomotor response (SVR) in patients with lateral epicondylitis.
To determine if alterations in SVR are associated with the pathogenesis of epicondylitis pain.
To explore the potential involvement of local sympathetic nervous system dysfunction.

Main Methods:

Utilized a laser Doppler flowmeter to measure blood flow velocity in the dermal microvascular bed.

Related Experiment Videos

Assessed SVR in the skin overlying the affected enthesis of 40 patients with lateral epicondylitis.

Compared SVR in affected areas with the unaffected contralateral epicondyle.

Main Results:

A significant association was found between the absence of a normal SVR and lateral epicondylitis.
The SVR was significantly reduced or absent in the skin of the affected enthesis compared to the unaffected side (P < 0.01).
These findings indicate a localized impairment in sympathetic vascular control.

Conclusions:

Local dysfunction of the sympathetic nervous system is associated with the pathogenesis of lateral epicondylitis.
Impaired SVR may contribute to the development or persistence of pain in epicondylitis.
Further research into neurovascular mechanisms could inform novel treatment strategies for enthesopathies.