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Acute postasthmatic amyotrophy (Hopkins' syndrome)
L J Liedholm1, O Eeg-Olofsson, B E Ekenberg
1Department of Clinical Neurophysiology, University Hospital, Uppsala, Sweden.
Muscle & Nerve
|July 1, 1994
Summary
Acute postasthmatic amyotrophy is a rare neurological condition. This disorder causes sudden limb paralysis about a week after an asthma attack, with unknown causes possibly involving immune responses.
Area of Science:
- Neurology
- Immunology
Background:
- Acute postasthmatic amyotrophy is a rare condition.
- Only 26 cases have been previously reported.
Observation:
- Characterized by sudden onset of flaccid paralysis in an arm or leg.
- Sensibility is completely preserved.
- Occurs approximately one week after an asthmatic attack.
Findings:
- The cause is likely a lesion of the anterior horn of the spinal cord.
- Evidence suggests a more widespread pathological process.
- The exact etiology remains unknown.
Implications:
- Suggests potential infectious or immunological mechanisms.
- Highlights a rare but significant neurological complication of asthma.
- Further research is needed to elucidate the underlying pathophysiology and develop targeted treatments.