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Updated: Aug 10, 2026
13:13
Biochemical Measurement of Neonatal Hypoxia
Published on: August 24, 2011
[Erythrocyte membrane function in intrauterine fetal hypoxia]
Akusherstvo I Ginekologiia
|January 1, 1993
Abstract:
Studies of the structural changes of erythrocytic phospholipids and their free-radical oxidation in health and intrauterine hypoxia in 61 parturients and their fetuses have shown that, despite a variety of causes of intrauterine hypoxia, the structural changes of fetal red cells are virtually the same and present as enlarged crystals and more marked crystallization of the phospholipid layer of the membrane. These structural changes occur in the presence of lipid peroxidation activation and antioxidant system insufficiency.
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01:14Erythropoiesis
Red blood cells (RBCs) transport oxygen to all body tissues. These cells survive only for 120 days and then need to be replenished. Erythropoiesis is the process of RBC production. In healthy individuals, erythropoiesis ensures all tissues are amply supplied with oxygen. In addition, blood loss due to injury leads to a drop in the physiological oxygen level that will cause erythropoiesis. Any defect in erythropoiesis leads to several physiological disorders, including thalassemia, anemia, and...
01:29Structure and Function of Erythrocytes
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01:22Lifecycle of Erythrocytes
Erythrocytes, also known as red blood cells, constantly move through blood capillaries. As a result, they damage their plasma membrane due to the continuous friction. Typically, after 100 to 120 days, erythrocytes become rigid and fragile as they wear out. As they pass through small vessels in the spleen and liver, they can get trapped and break apart into fragments.
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01:24Factors Affecting Erythropoiesis
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EPO then...
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01:23Hypoxia
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1. Anemic hypoxia: This type occurs due to insufficient oxygen delivery caused by a lack of red blood cells (RBCs) or RBCs with abnormal or...
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