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Reversed-phase chromatography of small molecules and peptides on a continuous rod of macroporous
Q C Wang1, F Svec, J M Fréchet
1Cornell University, Department of Chemistry, Baker Laboratory, Ithaca, NY 14853-1301.
Journal of Chromatography. A
|May 27, 1994
Abstract:
A continuous "molded" rod of porous poly(styrene-co-divinylbenzene) prepared by a bulk free radical polymerization within the confines of a chromatographic column has been used successfully for the reversed-phase HPLC of alkylbenzenes and peptides. An excellent rapid separation of bradykinin and [D-Phe7]-bradykinin with a molecular mass of about 1000 was also achieved.