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Postnatal development of nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) positive neurons in rat
D Tomić1, M Zobundźija, M Meáugorac
1Department of Anatomy, Histology and Embryology, Faculty of Veterinary Medicine, University of Zagreb, Croatia.
Abstract:
First nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d)-positive perikarya in rat prefrontal cortex (PFC) are present at birth. On postnatal day (P) 1, there is an increase of NADPH-d-positive neurons in all developing layers of PFC. From P1 to P7, a further increase in the overall number of positive neurons is observed. First laminar and area shifts are noted on P21, while morphological maturation of NADPH-d-positive neurons is finished around P30. In conclusion, the postnatal development of NADPH-d neurons in PFC is in concordance with other developmental events in rat cerebral cortex.